Rabix-IG is derived from the blood of horses. eRIG neutralize the virus at the wound site within a few hours. There are two types of Rabies Immunoglobulin, human (hRIG) and equine (eRIG). Both have similar clinical effectiveness in eliminating the virus at the wound site. Rabix-IG is given as an injection by a doctor or nurse. It provides immunization and is indicated in individuals with category III exposures (in depth injury). RIG neutralizes the rabies virus at the inoculation site on time before the immune system responds to the vaccine by production of rabies virus neutralizing antibodies. Both active (vaccine) and passive immunization (Immunoglobulin) prevent the rabies virus from infiltrating the central nervous system, but become ineffective once the virus has crossed into the central nervous system. Rabix-IG is administered only once in a lifetime. RIG administration is not indicated 7 days after the initial rabies vaccine administration. The most common side effects include nausea, acute toxicity, rash, and stomach upset. They do not normally last very long. Sitting or lying down can sometimes help. Consult your doctor if any of the side effects persist or worry you. Before having the injection, you should tell your doctor if you've ever had an allergic reaction to a immunoglobulin. Some other medicines may react with the equine rabies immunoglobulin so talk to your doctor about other medications you are taking as well. You should consult your doctor first if you are pregnant or breastfeeding.