Papilovax Injection - (0.5ml/dose)
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Ashik Medical
Price
৳2,250.00
৳2,500.00
/pc
-10%
Club Point:
200
Refund
Not Applicable
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Indication
Human Papillomavirus infection, Premalignant cervical lesions and cervical cancer, Adenocarcinoma in situ, Cervical intraepithelial neoplasia
Administration
Inject IM in deltoid region of upper arm
Adult Dose
Intramuscular Cervical Cancer Prevention Indicated for prevention of cervical precancers and cervical cancer associated with oncogenic HPV types 16 and 18 Girls and women (9-25 years old): 0.5 mL IM x3 doses at 0, 1, and 6 months (FDA approved labeled dose) CDC recommendations Girls and women aged 9-26 years: 0.5 mL IM for 3 doses administered at schedule of 0, 2, and 6 mo
Child Dose
Child: Not recommended for use in girls below 9 yr of age. Intramuscular Cervical Cancer Prevention Indicated for prevention of cervical precancers and cervical cancer associated with oncogenic HPV types 16 and 18 Girls and women (9-25 years old): 0.5 mL IM x3 doses at 0, 1, and 6 months (FDA approved labeled dose) CDC recommendations Girls and women aged 9-26 years: 0.5 mL IM for 3 doses administered at schedule of 0, 2, and 6 mo
Contraindication
Known hypersensitivity to any component. Postpone admin in patient suffering from an acute febrile illness.
Mode of Action
Human Papillomavirus (HPV) type 16 and 18 cause about 70% of cervical cancer. HPV bivalent (types 16 and 18) vaccine is a non-infectious vaccine produced by recombinant technology, which contains virus-like particles (VLP) of the major capsid L1 protein of oncogenic HPV types 16 and 18. Efficacy of vaccine may be mediated by the production of IgG neutralizing antibodies against the HPV-L1 capsid proteins.
Precaution
Observe patient for 15 min after admin as syncope, sometimes accompanied by transient tonic clonic movements and other seizure-like activity may occur during recovery. Caution in patients with thrombocytopenia or other coagulation disorders as IM admin can cause bleeding. Not to be administered by IV, SC, or intradermal route. Immunocompromised individuals may have diminished immune response to the vaccine. As vaccination will not provide protection against every HPV infection or existing HPV infections, routine cervical screening should still be performed. Not recommended for use during pregnancy; caution in lactation. Lactation: Unknown whether distributed in breast milk; use with caution
Side Effect
>10% Injection site pain, erythema, and inflammation Fatigue,Headache,Myalgia,GI symptoms,Arthralgia
Pregnancy Category Note
Pregnancy category: B; Not recommended for use in pregnant women Women who become pregnant after initiating the vaccination series, no intervention is needed; delay the remaining doses until completion of pregnancy
Interaction
Immunosuppressive therapies e.g. irradiation, cytotoxic drugs and corticorsteroids may reduce a patient's immune response to the vaccine.
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