Jonort is a distinctive formulation comprising a standardized extract of St. John's Wort, renowned for its efficacy in herbal medicine for treating depression. St. John's Wort is rich in active constituents like hypericin, hyperforin, hyperoside, quercitrin, and vitamin C. The antidepressant properties of Jonort involve the inhibition of neurotransmitter re-uptake, including serotonin, dopamine, noradrenaline, γ-aminobutyric acid (GABA), and L-glutamate. Additionally, it exhibits inhibitory effects on Monoamine oxidase (MAO) and catechol-O-methyltransferase (COMT).