INTRODUCTION

ERYPEG 50MCG INJECTION(PFS) contains Pegylated Recombinant Human Erythropoietin which belongs to the group of medicines called Erythropoiesis-stimulating agents. It is used to treat anemia caused due to chronic kidney disease (CKD), chemotherapy, anti-viral therapy (Ex. zidovudine), blood donation or due to any bone marrow disorders/cancers (such as myelodysplastic syndromes).

It can also be used to prevent or manage anemia in patients who are planning to undergo any major bone surgery (such as hip or knee replacement operations). It may also reduce the potential need for blood transfusion in cancer patients and in patients undergoing bone surgery or chemotherapy.

ERYPEG 50MCG INJECTION(PFS) is suitable for use both in adults and in children. During treatment with ERYPEG 50MCG INJECTION(PFS) your doctor will constantly monitor your blood pressure and iron levels in blood and will adjust the dose accordingly to avoid the risk of unwanted side effects.

Before receiving ERYPEG 50MCG INJECTION(PFS) inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have high blood pressure, diabetes, obesity, breast cancer, head and neck cancer, fits, previous history of blood clots or if you are undergoing dialysis or any surgery as a precaution.

ERYPEG 50MCG INJECTION(PFS) is not recommended for use in patients with recent heart attack or stroke. It is also not suitable for use in patients having severe uncontrollable high blood pressure and pure red aplastic anemia (a condition in which the bone marrow cannot produce RBC).

Inform your doctor before receiving ERYPEG 50MCG INJECTION(PFS) if you are pregnant or breastfeeding as a precaution. The most common side effects of receiving ERYPEG 50MCG INJECTION(PFS) are diarrhea, nausea, vomiting, fever, stuffy nose and sore throat. Contact your doctor if any of these side effect worsens.

USES OF ERYPEG 50MCG INJECTION(PFS)

It is used in adults and in children to treat:

• Anemia (low RBC in blood) caused due to chronic kidney disease, chemotherapy, anti-viral therapy (Ex. zidovudine), blood donation or any bone marrow disorders/cancers (such as myelodysplastic syndromes)
• Prevent or manage anemia in patients undergoing any major bone surgery (such as hip or knee replacement operations)
• Reduce the need for blood transfusion in cancer patients and in patients undergoing bone surgery or chemotherapy

HOW ERYPEG 50MCG INJECTION(PFS) WORKS

ERYPEG 50MCG INJECTION(PFS) is an Erythropoiesis-stimulating agent. Following administration, it stimulates the bone marrow to produce red blood cells. It contains a medicine called Pegylated Recombinant Human Erythropoietin which acts similar to the endogenous human protein called erythropoietin (a substance that stimulates bone marrow to produce red blood cells).

Therefore, it replaces the lost red blood cells (RBC) in the body of anaemic patients and in patients who are at risk of developing anemia due to chemotherapy, anti-viral therapy or bone marrow disorders.